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Nuclear receptor corepressors Ncor1 and Ncor2 (Smrt) are required for retinoic acid-dependent repression of Fgf8 during somitogenesis

Retinoic acid (RA) repression of Fgf8 is required for many different aspects of organogenesis, however relatively little is known about how endogenous RA controls gene repression as opposed to gene activation. Here, we show that nuclear receptor corepressors NCOR1 and NCOR2 (SMRT) redundantly mediat...

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Bibliografiske detaljer
Udgivet i:Dev Biol
Main Authors: Kumar, Sandeep, Cunningham, Thomas J., Duester, Gregg
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031541/
https://ncbi.nlm.nih.gov/pubmed/27506116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.08.005
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