Retinoic acid controls body axis extension by directly repressing Fgf8 transcription

Retinoic acid (RA) generated in the mesoderm of vertebrate embryos controls body axis extension by downregulating Fgf8 expression in cells exiting the caudal progenitor zone. RA activates transcription by binding to nuclear RA receptors (RARs) at RA response elements (RAREs), but it is unknown wheth...

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Detaylı Bibliyografya
Asıl Yazarlar: Kumar, Sandeep, Duester, Gregg
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2014
Konular:
Research Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197666/
https://ncbi.nlm.nih.gov/pubmed/25053430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.112367
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