Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia

Fungal infections have skyrocketed in immune-compromised patients lacking CD4(+) T cells, underscoring the need for vaccine prevention. An understanding of the elements that promote vaccine immunity in this setting is essential. We previously demonstrated that vaccine-induced IL-17A(+) CD8(+) T cell...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Autores principales: Nanjappa, Som Gowda, Hernández-Santos, Nydiaris, Galles, Kevin, Wüthrich, Marcel, Suresh, M., Klein, Bruce S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569330/
https://ncbi.nlm.nih.gov/pubmed/26367276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005161
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