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Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia
Fungal infections have skyrocketed in immune-compromised patients lacking CD4(+) T cells, underscoring the need for vaccine prevention. An understanding of the elements that promote vaccine immunity in this setting is essential. We previously demonstrated that vaccine-induced IL-17A(+) CD8(+) T cell...
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| Publié dans: | PLoS Pathog |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4569330/ https://ncbi.nlm.nih.gov/pubmed/26367276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005161 |
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