Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression

5-Fluorouracil (5-FU) is a key drug for the treatment of esophageal squamous cell carcinoma (ESCC); however, resistance to it remains a critical limitation to its clinical use. To clarify the mechanisms of 5-FU resistance of ESCC, we originally established 5-FU-resistant ESCC cells, TE-5R, by step-w...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Kikuchi, Osamu, Ohashi, Shinya, Nakai, Yukie, Nakagawa, Shunsaku, Matsuoka, Kazuaki, Kobunai, Takashi, Takechi, Teiji, Amanuma, Yusuke, Yoshioka, Masahiro, Ida, Tomomi, Yamamoto, Yoshihiro, Okuno, Yasushi, Miyamoto, Shin’ichi, Nakagawa, Hiroshi, Matsubara, Kazuo, Chiba, Tsutomu, Muto, Manabu
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568778/
https://ncbi.nlm.nih.gov/pubmed/26396918
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