Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

BACKGROUND: Epidermal growth factor receptor (EGFR) plays a pivotal role in the pathophysiology of esophageal squamous cell carcinoma (ESCC). However, the clinical effects of EGFR inhibitors on ESCC are controversial. This study sought to identify the factors determining the therapeutic efficacy of...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Yoshioka, Masahiro, Ohashi, Shinya, Ida, Tomomi, Nakai, Yukie, Kikuchi, Osamu, Amanuma, Yusuke, Matsubara, Junichi, Yamada, Atsushi, Miyamoto, Shin’ichi, Natsuizaka, Mitsuteru, Nakagawa, Hiroshi, Chiba, Tsutomu, Seno, Hiroshi, Muto, Manabu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540425/
https://ncbi.nlm.nih.gov/pubmed/28764725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0572-7
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