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New Approaches to Target the Mycolic Acid Biosynthesis Pathway for the Development of Tuberculosis Therapeutics

Mycolic acids are the major lipid component of the unique mycobacterial cell wall responsible for the protection of the tuberculosis bacilli from many outside threats. Mycolic acids are synthesized in the cytoplasm and transported to the outer membrane as trehalose-containing glycolipids before bein...

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Detalhes bibliográficos
Publicado no:Curr Pharm Des
Main Authors: North, E. Jeffrey, Jackson, Mary, Lee, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568743/
https://ncbi.nlm.nih.gov/pubmed/24245756
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