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Cohesin recruits the Esco1 acetyltransferase genome wide to repress transcription and promote cohesion in somatic cells

The cohesin complex links DNA molecules and plays key roles in the organization, expression, repair, and segregation of eukaryotic genomes. In vertebrates the Esco1 and Esco2 acetyltransferases both modify cohesin’s Smc3 subunit to establish sister chromatid cohesion during S phase, but differ in th...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Rahman, Sadia, Jones, Mathew J. K., Jallepalli, Prasad V.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568707/
https://ncbi.nlm.nih.gov/pubmed/26305936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505323112
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