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Cohesin recruits the Esco1 acetyltransferase genome wide to repress transcription and promote cohesion in somatic cells
The cohesin complex links DNA molecules and plays key roles in the organization, expression, repair, and segregation of eukaryotic genomes. In vertebrates the Esco1 and Esco2 acetyltransferases both modify cohesin’s Smc3 subunit to establish sister chromatid cohesion during S phase, but differ in th...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568707/ https://ncbi.nlm.nih.gov/pubmed/26305936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505323112 |
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