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Playing POLO-like kinase in NRAS mutant melanoma
NRAS-mutant melanomas are extremely aggressive and highly resistant to currently available therapeutic modalities. Hence, new targets and therapeutic strategies for NRAS-driven melanomas are needed. As blocking NRAS directly has not been possible thus far, targeting downstream NRAS effectors, such a...
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| Publicado no: | J Invest Dermatol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568563/ https://ncbi.nlm.nih.gov/pubmed/26358384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.253 |
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