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Metabolic fate of endogenous molecular damage: Urinary glutathione conjugates of DNA-derived base propenals as markers of inflammation

Although mechanistically linked to disease, cellular molecules damaged by endogenous processes have not emerged as significant biomarkers of inflammation and disease risk, due in part to poor understanding of their pharmacokinetic fate from tissue to excretion. Here, we use systematic metabolite pro...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jumpathong, Watthanachai, Chan, Wan, Taghizadeh, Koli, Babu, I. Ramesh, Dedon, Peter C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568270/
https://ncbi.nlm.nih.gov/pubmed/26283391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503945112
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