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Small cyclic agonists of iron regulatory hormone hepcidin

Minihepcidins are in vitro and in vivo active mimetics of iron-regulatory hormone hepcidin. They contain various unusual amino acids including: N-substituted, β-homo-, and D-amino acids with their combination depending on particular minihepcidin. In the current study, we sought to limit the use of u...

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Détails bibliographiques
Publié dans:Bioorg Med Chem Lett
Auteurs principaux: Chua, Kristine, Fung, Eileen, Micewicz, Ewa D., Ganz, Tomas, Nemeth, Elizabeta, Ruchala, Piotr
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567957/
https://ncbi.nlm.nih.gov/pubmed/25813158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.03.012
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