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Cellular Catabolism of the Iron-Regulatory Peptide Hormone Hepcidin

Hepcidin, a 25-amino acid peptide hormone, is the principal regulator of plasma iron concentrations. Hepcidin binding to its receptor, the iron exporter ferroportin, induces ferroportin internalization and degradation, thus blocking iron efflux from cells into plasma. The aim of this study was to ch...

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Main Authors: Preza, Gloria Cuevas, Pinon, Rogelio, Ganz, Tomas, Nemeth, Elizabeta
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594189/
https://ncbi.nlm.nih.gov/pubmed/23536837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058934
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