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Cellular Catabolism of the Iron-Regulatory Peptide Hormone Hepcidin

Hepcidin, a 25-amino acid peptide hormone, is the principal regulator of plasma iron concentrations. Hepcidin binding to its receptor, the iron exporter ferroportin, induces ferroportin internalization and degradation, thus blocking iron efflux from cells into plasma. The aim of this study was to ch...

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Autors principals: Preza, Gloria Cuevas, Pinon, Rogelio, Ganz, Tomas, Nemeth, Elizabeta
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594189/
https://ncbi.nlm.nih.gov/pubmed/23536837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058934
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