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Understanding the Structure/Activity Relationships of the Iron Regulatory Peptide Hepcidin
The peptide hormone hepcidin is a key homeostatic regulator of iron metabolism and involved in pathological regulation of iron in response to infection, inflammation, hypoxia and anaemia. It acts by binding to the iron exporter ferroportin, causing it to be internalised and degraded; however, little...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073735/ https://ncbi.nlm.nih.gov/pubmed/21439478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.12.009 |
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