IL-27 suppresses antimicrobial activity in human leprosy

The mechanisms by which intracellular pathogens trigger immunosuppressive pathways are critical for understanding the pathogenesis of microbial infection. One pathway that inhibits host defense responses involves the induction of type I interferons and subsequently IL-10, yet the mechanism by which...

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Bibliografiske detaljer
Udgivet i:J Invest Dermatol
Main Authors: Teles, Rosane M. B., Kelly-Scumpia, Kindra M., Sarno, Euzenir N., Rea, Thomas H., Ochoa, Maria T., Cheng, Genhong, Modlin, Robert L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567935/
https://ncbi.nlm.nih.gov/pubmed/26030183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.195
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