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Advances in measuring single-cell pharmacokinetics and pharmacology in vivo

Measuring key pharmacokinetic and pharmacodynamic parameters in vivo at the single cell level is likely to enhance drug discovery and development. In this review, we summarize recent advances in this field and highlight current and future capabilities.

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Detalhes bibliográficos
Publicado no:Drug Discov Today
Main Authors: Vinegoni, Claudio, Dubach, John M., Thurber, Greg M., Miller, Miles A., Mazitschek, Ralph, Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567932/
https://ncbi.nlm.nih.gov/pubmed/26024776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2015.05.011
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