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Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo
Pharmacokinetic analysis at the organ level provides insight into how drugs distribute throughout the body but cannot explain how drugs work at the cellular level. Here we demonstrate in vivo single cell pharmacokinetic imaging of PARP-1 inhibitors (PARPi) and model drug behavior under varying condi...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579506/ https://ncbi.nlm.nih.gov/pubmed/23422672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2506 |
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