XL888 limits vemurafenib-induced proliferative skin events by suppressing paradoxical MAPK activation

Lignende værker

• Paradoxical oncogenesis and the long term consequences of BRAF inhibition in melanoma
  af: Gibney, Geoffrey T., et al.
  Udgivet: (2013)
• Inhibition of Wee1, AKT and CDK4 underlies the efficacy of the HSP90 inhibitor XL888 in an in vivo model of NRAS mutant melanoma
  af: Haarberg, H. Eirik, et al.
  Udgivet: (2013)
• NRAS mutant melanoma: biological behavior and future strategies for therapeutic management
  af: Fedorenko, Inna V., et al.
  Udgivet: (2012)
• The heat shock protein-90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms
  af: Paraiso, Kim H. T., et al.
  Udgivet: (2012)
• Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma
  af: Rebecca, Vito W., et al.
  Udgivet: (2014)