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Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells
BACKGROUND: Ursolic acid (UA), a pentacyclic triterpenoid, is known to have anti-tumor activity in various cancers including human non small cell lung cancer (NSCLC). However, the molecular mechanisms underlying the action of UA remain largely unknown. METHODS: Cell viability was measured by MTT ass...
Guardat en:
| Publicat a: | J Exp Clin Cancer Res |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567809/ https://ncbi.nlm.nih.gov/pubmed/26362062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0215-9 |
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