Baicalein increases the expression and reciprocal interplay of RUNX3 and FOXO3a through crosstalk of AMPKα and MEK/ERK1/2 signaling pathways in human non-small cell lung cancer cells

BACKGROUND: Baicalein, a natural flavonoid obtained from the Scutellaria baicalensis root, has been reported to inhibit growth of human lung cancer. However, the detailed mechanism underlying this has not been well elucidated. METHODS: Cell viability was measured using a 3-(4, 5-dimethylthiazol-2-yl...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Zheng, Fang, Wu, Jingjing, Zhao, Shunyu, Luo, Qingmei, Tang, Qing, Yang, LiJun, Li, Liuning, Wu, WanYing, Hann, Swei Sunny
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457308/
https://ncbi.nlm.nih.gov/pubmed/25948105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0160-7
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