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Inactivation of Stat3 and crosstalk of miRNA155-5p and FOXO3a contribute to the induction of IGFBP1 expression by beta-elemene in human lung cancer

β-Elemene, an active component of natural plants, has been shown to exhibit anticancer properties. However, the detailed mechanism underlying these effects has yet to be determined. In this study, we show that β-elemene inhibits the growth of lung cancer cells. Mechanistically, we found that β-eleme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Mol Med
Hauptverfasser: Zheng, Fang, Tang, Qing, Zheng, Xiao-hua, Wu, JingJing, Huang, HaiDing, Zhang, Haibo, Hann, Swei Sunny
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135838/
https://ncbi.nlm.nih.gov/pubmed/30209296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0146-6
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