Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor

Legionella pneumophila is a bacterial pathogen that thrives in alveolar macrophages, causing a severe pneumonia. The virulence of L. pneumophila depends on its Dot/Icm type IV secretion system (T4SS), which delivers more than 300 effector proteins into the host, where they rewire cellular signaling...

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Pubblicato in:Infect Immun
Autori principali: Schroeder, Gunnar N., Aurass, Philipp, Oates, Clare V., Tate, Edward W., Hartland, Elizabeth L., Flieger, Antje, Frankel, Gad
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567653/
https://ncbi.nlm.nih.gov/pubmed/26216420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00785-15
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