The Legionella pneumophila Dot/Icm-secreted Effector PlcC/CegC1 Together with PlcA and PlcB Promotes Virulence and Belongs to a Novel Zinc Metallophospholipase C Family Present in Bacteria and Fungi

Legionella pneumophila is a water-borne bacterium that causes pneumonia in humans. PlcA and PlcB are two previously defined L. pneumophila proteins with homology to the phosphatidylcholine-specific phospholipase C (PC-PLC) of Pseudomonas fluorescens. Additionally, we found that Lpg0012 shows similar...

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Bibliografske podrobnosti
Main Authors: Aurass, Philipp, Schlegel, Maren, Metwally, Omar, Harding, Clare R., Schroeder, Gunnar N., Frankel, Gad, Flieger, Antje
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630882/
https://ncbi.nlm.nih.gov/pubmed/23457299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.426049
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