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LtpD Is a Novel Legionella pneumophila Effector That Binds Phosphatidylinositol 3-Phosphate and Inositol Monophosphatase IMPA1

The Dot/Icm type IV secretion system (T4SS) of Legionella pneumophila is crucial for the pathogen to survive in protozoa and cause human disease. Although more than 275 effector proteins are delivered into the host cell by the T4SS, the function of the majority is unknown. Here we have characterized...

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Main Authors: Harding, Clare R., Mattheis, Corinna, Mousnier, Aurélie, Oates, Clare V., Hartland, Elizabeth L., Frankel, Gad, Schroeder, Gunnar N.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811825/
https://ncbi.nlm.nih.gov/pubmed/24002062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01054-13
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