Pseudomonas aeruginosa Quorum Sensing Molecule N-(3-Oxododecanoyl)-l-Homoserine-Lactone Induces HLA-G Expression in Human Immune Cells

HLA-G is a nonclassical class I human leukocyte antigen (HLA) involved in mechanisms of immune tolerance. The objective of this study was to determine whether N-(3-oxododecanoyl)-l-homoserine lactone (3O-C(12)-HSL), a quorum sensing molecule produced by Pseudomonas aeruginosa, could modify HLA-G exp...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Bortolotti, Daria, LeMaoult, Joel, Trapella, Claudio, Di Luca, Dario, Carosella, Edgardo D., Rizzo, Roberta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567644/
https://ncbi.nlm.nih.gov/pubmed/26195547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00803-15
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