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Presenilin-1 familial Alzheimer’s disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice

Aberrations in hippocampal neurogenesis are associated with learning and memory, synaptic plasticity and neurodegeneration in Alzheimer’s disease (AD). However, the linkage between them, β-amyloidosis and neuroinflammation is not well understood. To this end, we generated a mouse overexpressing fami...

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Dettagli Bibliografici
Pubblicato in:Brain Behav Immun
Autori principali: Kiyota, Tomomi, Morrison, Christine M, Tu, Guihua, Dyavarshetty, Bhagyalaxmi, Weir, Robert A, Zhang, Gang, Xiong, Huangui, Gendelman, Howard E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567522/
https://ncbi.nlm.nih.gov/pubmed/26112421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.06.014
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