Presenilin-1 familial Alzheimer’s disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice

Aberrations in hippocampal neurogenesis are associated with learning and memory, synaptic plasticity and neurodegeneration in Alzheimer’s disease (AD). However, the linkage between them, β-amyloidosis and neuroinflammation is not well understood. To this end, we generated a mouse overexpressing fami...

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Detalles Bibliográficos
Publicado en:Brain Behav Immun
Main Authors: Kiyota, Tomomi, Morrison, Christine M, Tu, Guihua, Dyavarshetty, Bhagyalaxmi, Weir, Robert A, Zhang, Gang, Xiong, Huangui, Gendelman, Howard E
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567522/
https://ncbi.nlm.nih.gov/pubmed/26112421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.06.014
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