Nociception and inflammatory hyperalgesia evaluated in rodents using infrared laser stimulation after Trpv1 gene knockout or resiniferatoxin lesion

TRPV1 is expressed in a subpopulation of myelinated Aδ and unmyelinated C-fibers. TRPV1(+) fibers are essential for the transmission of nociceptive thermal stimuli and for the establishment and maintenance of inflammatory hyperalgesia. We have previously shown that high-power, short-duration pulses...

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Bibliographic Details
Published in:Pain
Main Authors: Mitchell, Kendall, Lebovitz, Evan E., Keller, Jason M., Mannes, Andrew J., Nemenov, Michael I., Iadarola, Michael J.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567256/
https://ncbi.nlm.nih.gov/pubmed/24434730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2014.01.007
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