Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates

BACKGROUND: Ablation of TRPV1-expressing nociceptive fibers with the potent capsaicin analog resiniferatoxin (RTX) results in long lasting pain relief. RTX is particularly adaptable to focal application, and the induced chemical axonopathy leads to analgesia with a duration that is influenced by dos...

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Bibliografski detalji
Glavni autori: Mitchell, Kendall, Bates, Brian D, Keller, Jason M, Lopez, Matthew, Scholl, Lindsey, Navarro, Julia, Madian, Nicholas, Haspel, Gal, Nemenov, Michael I, Iadarola, Michael J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019206/
https://ncbi.nlm.nih.gov/pubmed/21167052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-94
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