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Resiniferatoxin (RTX) Causes a Uniquely Protracted Musculoskeletal Hyperalgesia in Mice by Activation of TRPV1 Receptors

Inactivation of TRPV1 receptors is one approach to analgesic drug development. However, TRPV1 receptors exert different effects on each modality of pain. Because muscle pain is clinically important, we compared the effect of TRPV1 ligands on musculoskeletal nociception to that on thermal and tactile...

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Detalhes bibliográficos
Main Authors: Abdelhamid, Ramy E., Kovács, Katalin J., Honda, Christopher N., Nunez, Myra G., Larson, Alice A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881420/
https://ncbi.nlm.nih.gov/pubmed/24188863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.07.021
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