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Effect of Farnesyltransferase Inhibitor R115777 on Mitochondria of Plasmodium falciparum

The parasite Plasmodium falciparum causes severe malaria and is the most dangerous to humans. However, it exhibits resistance to their drugs. Farnesyltransferase has been identified in pathogenic protozoa of the genera Plasmodium and the target of farnesyltransferase includes Ras family. Therefore,...

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Bibliographic Details
Published in:Korean J Parasitol
Main Authors: Ha, Young Ran, Hwang, Bae-Geun, Hong, Yeonchul, Yang, Hye-Won, Lee, Sang Joon
Format: Artigo
Language:Inglês
Published: The Korean Society for Parasitology and Tropical Medicine 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566515/
https://ncbi.nlm.nih.gov/pubmed/26323840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3347/kjp.2015.53.4.421
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