Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers

AIMS: Nebulette is a 109 kDa modular protein localized in the sarcomeric Z-line of the heart. In vitro studies have suggested a role of nebulette in stabilizing the thin filament, and missense mutations in the nebulette gene were recently shown to be causative for dilated cardiomyopathy and endocard...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Mastrototaro, Giuseppina, Liang, Xingqun, Li, Xiaodong, Carullo, Pierluigi, Piroddi, Nicoletta, Tesi, Chiara, Gu, Yusu, Dalton, Nancy D., Peterson, Kirk L., Poggesi, Corrado, Sheikh, Farah, Chen, Ju, Bang, Marie-Louise
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565986/
https://ncbi.nlm.nih.gov/pubmed/25987543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv156
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