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Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle
Mavacamten (MYK-461) is a small-molecule allosteric inhibitor of sarcomeric myosins being used in preclinical/clinical trials for hypertrophic cardiomyopathy treatment. A better understanding of its impact on force generation in intact or skinned striated muscle preparations, especially for human ca...
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| 出版年: | J Gen Physiol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8077167/ https://ncbi.nlm.nih.gov/pubmed/33891673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012789 |
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