Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle

Tension development and relaxation in cardiac muscle are regulated at the thin filament via Ca(2+) binding to cardiac troponin C (cTnC) and strong cross-bridge binding. However, the influence of cTnC Ca(2+)-binding properties on these processes in the organized structure of cardiac sarcomeres is not...

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Bibliografiset tiedot
Päätekijät: Kreutziger, Kareen L., Piroddi, Nicoletta, McMichael, Jonathan T., Tesi, Chiara, Poggesi, Corrado, Regnier, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018540/
https://ncbi.nlm.nih.gov/pubmed/21035455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.10.025
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