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Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle
Tension development and relaxation in cardiac muscle are regulated at the thin filament via Ca(2+) binding to cardiac troponin C (cTnC) and strong cross-bridge binding. However, the influence of cTnC Ca(2+)-binding properties on these processes in the organized structure of cardiac sarcomeres is not...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018540/ https://ncbi.nlm.nih.gov/pubmed/21035455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.10.025 |
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