Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1

Phosphoglycerate kinase 1 (PGK1) catalyzes the reversible transfer of a phosphoryl group from 1, 3-bisphosphoglycerate (1, 3-BPG) to ADP, producing 3-phosphoglycerate (3-PG) and ATP. PGK1 plays a key role in coordinating glycolytic energy production with one-carbon metabolism, serine biosynthesis, a...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Wang, Shiwen, Jiang, Bowen, Zhang, Tengfei, Liu, Lixia, Wang, Yi, Wang, Yiping, Chen, Xiufei, Lin, Huaipeng, Zhou, Lisha, Xia, Yukun, Chen, Leilei, Yang, Chen, Xiong, Yue, Ye, Dan, Guan, Kun-Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565669/
https://ncbi.nlm.nih.gov/pubmed/26356530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002243
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