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mTOR: a pharmacologic target for autophagy regulation

mTOR, a serine/threonine kinase, is a master regulator of cellular metabolism. mTOR regulates cell growth and proliferation in response to a wide range of cues, and its signaling pathway is deregulated in many human diseases. mTOR also plays a crucial role in regulating autophagy. This Review provid...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Kim, Young Chul, Guan, Kun-Liang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382265/
https://ncbi.nlm.nih.gov/pubmed/25654547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73939
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