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mTOR: a pharmacologic target for autophagy regulation
mTOR, a serine/threonine kinase, is a master regulator of cellular metabolism. mTOR regulates cell growth and proliferation in response to a wide range of cues, and its signaling pathway is deregulated in many human diseases. mTOR also plays a crucial role in regulating autophagy. This Review provid...
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| Published in: | J Clin Invest |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382265/ https://ncbi.nlm.nih.gov/pubmed/25654547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73939 |
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