Catalytically active guanylyl cyclase-B requires glycosylation and mutations that inhibit this process cause dwarfism

Míreanna Comhchosúla

• Catalytically Active Guanylyl Cyclase B Requires Endoplasmic Reticulum-mediated Glycosylation, and Mutations That Inhibit This Process Cause Dwarfism
  le: Dickey, Deborah M., et al.
  Foilsithe: (2016)
• Skeletal overgrowth-causing mutations mimic an allosterically activated conformation of guanylyl cyclase-B that is inhibited by 2,4,6,-trinitrophenyl ATP
  le: Dickey, Deborah M., et al.
  Foilsithe: (2017)
• Mutation of a conserved lysine in the kinase homology domain reduces the natriuretic peptide-dependent activity and phosphorylation of guanylyl cyclase-A
  le: Edmund, Aaron B, et al.
  Foilsithe: (2015)
• Prevention of guanylyl cyclase–B dephosphorylation rescues achondroplastic dwarfism
  le: Wagner, Brandon M., et al.
  Foilsithe: (2021)
• ProBNP(1–108) Is Resistant to Degradation and Activates Guanylyl Cyclase-A with Reduced Potency
  le: Dickey, Deborah M., et al.
  Foilsithe: (2011)