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Lipoprotein Lipase is an Important Modulator of Lipid Uptake and Storage in Hypothalamic Neurons

LPL is the rate-limiting enzyme for uptake of TG-derived FFA in peripheral tissues, and the enzyme is expressed in the brain and CNS. We previously created a mouse which lacks neuronal LPL. This animal becomes obese on a standard chow, and we observed reduced lipid uptake in the hypothalamus at 3 mo...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Libby, Andrew E., Wang, Hong, Mittal, Richa, Sungelo, Mitchell, Potma, Eric, Eckel, Robert H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565155/
https://ncbi.nlm.nih.gov/pubmed/26265042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.08.026
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