Loading...

Lipoprotein Lipase is an Important Modulator of Lipid Uptake and Storage in Hypothalamic Neurons

LPL is the rate-limiting enzyme for uptake of TG-derived FFA in peripheral tissues, and the enzyme is expressed in the brain and CNS. We previously created a mouse which lacks neuronal LPL. This animal becomes obese on a standard chow, and we observed reduced lipid uptake in the hypothalamus at 3 mo...

Full description

Saved in:
Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Libby, Andrew E., Wang, Hong, Mittal, Richa, Sungelo, Mitchell, Potma, Eric, Eckel, Robert H.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565155/
https://ncbi.nlm.nih.gov/pubmed/26265042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.08.026
Tags: Add Tag
No Tags, Be the first to tag this record!