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Lipoprotein Lipase is an Important Modulator of Lipid Uptake and Storage in Hypothalamic Neurons
LPL is the rate-limiting enzyme for uptake of TG-derived FFA in peripheral tissues, and the enzyme is expressed in the brain and CNS. We previously created a mouse which lacks neuronal LPL. This animal becomes obese on a standard chow, and we observed reduced lipid uptake in the hypothalamus at 3 mo...
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| Publié dans: | Biochem Biophys Res Commun |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565155/ https://ncbi.nlm.nih.gov/pubmed/26265042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.08.026 |
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