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Reg4-Induced Mitogenesis Involves Akt-GSK3β-β-Catenin-TCF-4 Signaling in Human Colorectal Cancer
Upregulation of regenerating gene 4 (Reg4) is observed in many human gastrointestinal malignancies including colorectal cancer (CRC). We previously reported a Reg4-mediated induction of epidermal growth factor receptor-Akt-AP1 signaling regulating CRC cell apoptosis. However, the role of Reg4 in the...
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| Udgivet i: | Mol Carcinog |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565142/ https://ncbi.nlm.nih.gov/pubmed/24151146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22088 |
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