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Genotype–Phenotype Correlations in Ornithine Transcarbamylase Deficiency: A Mutation Update

Ornithine transcarbamylase (OTC) deficiency is an X-linked trait that accounts for nearly half of all inherited disorders of the urea cycle. OTC is one of the enzymes common to both the urea cycle and the bacterial arginine biosynthesis pathway; however, the role of OTC has changed over evolution. F...

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Detalhes bibliográficos
Publicado no:J Genet Genomics
Main Authors: Caldovic, Ljubica, Abdikarim, Iman, Narain, Sahas, Tuchman, Mendel, Morizono, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565140/
https://ncbi.nlm.nih.gov/pubmed/26059767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2015.04.003
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