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A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase

Transcarbamylases catalyze the transfer of the carbamyl group from carbamyl phosphate (CP) to an amino group of a second substrate such as aspartate, ornithine, or putrescine. Previously, structural determination of a transcarbamylase from Xanthomonas campestris led to the discovery of a novel N-ace...

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Bibliografiset tiedot
Päätekijät: Shi, Dashuang, Yu, Xiaolin, Cabrera-Luque, Juan, Chen, Tony Y., Roth, Lauren, Morizono, Hiroki, Allewell, Norma M., Tuchman, Mendel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203365/
https://ncbi.nlm.nih.gov/pubmed/17600144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072919907
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