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Reversible Post-Translational Carboxylation Modulates The Enzymatic Activity Of N-Acetyl-L-Ornithine Transcarbamylase

N-acetyl-L-ornithine transcarbamylase (AOTCase), rather than ornithine transcarbamylase (OTCase), is the essential carbamylase enzyme in the arginine biosynthesis of several plant and human pathogens. The specificity of this unique enzyme provides a potential target for controlling the spread of the...

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Bibliographic Details
Main Authors: Li, Yongdong, Yu, Xiaolin, Ho, Jeremy, Fushman, David, Allewell, Norma M., Tuchman, Mendel, Shi, Dashuang
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959125/
https://ncbi.nlm.nih.gov/pubmed/20695527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1007386
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