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Mechanism of Allosteric Inhibition of N-Acetyl-L-glutamate Synthase by L-Arginine
N-Acetylglutamate synthase (NAGS) catalyzes the first committed step in l-arginine biosynthesis in plants and micro-organisms and is subject to feedback inhibition by l-arginine. This study compares the crystal structures of NAGS from Neisseria gonorrhoeae (ngNAGS) in the inactive T-state with l-arg...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643497/ https://ncbi.nlm.nih.gov/pubmed/19095660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805348200 |
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