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In silico feedback for in vivo regulation of a gene expression circuit
We show that difficulties in regulating cellular behavior with synthetic biological circuits may be circumvented using in silico feedback control. By tracking a circuit's output in Saccharomyces cerevisiae in real time, we precisely control its behavior using an in silico feedback algorithm to...
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| Udgivet i: | Nat Biotechnol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565053/ https://ncbi.nlm.nih.gov/pubmed/22057053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2018 |
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