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Iterative experiment design guides the characterization of a light-inducible gene expression circuit

Systems biology rests on the idea that biological complexity can be better unraveled through the interplay of modeling and experimentation. However, the success of this approach depends critically on the informativeness of the chosen experiments, which is usually unknown a priori. Here, we propose a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ruess, Jakob, Parise, Francesca, Milias-Argeitis, Andreas, Khammash, Mustafa, Lygeros, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491780/
https://ncbi.nlm.nih.gov/pubmed/26085136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423947112
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