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Dynamic disorder in simple enzymatic reactions induces stochastic amplification of substrate

A growing amount of evidence over the last two decades points to the fact that many enzymes exhibit fluctuations in their catalytic activity, which are associated with conformational changes on a broad range of timescales. The experimental study of this phenomenon, termed dynamic disorder, has becom...

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Publicat a:J R Soc Interface
Autors principals: Gupta, Ankit, Milias-Argeitis, Andreas, Khammash, Mustafa
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550977/
https://ncbi.nlm.nih.gov/pubmed/28747400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2017.0311
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