Dynamics of the BH3-Only Protein Binding Interface of Bcl-xL

The balance and interplay between pro-death and pro-survival members of the B-cell lymphoma-2 (Bcl-2) family proteins play key roles in regulation of the mitochondrial pathway of programmed cell death. Recent NMR and biochemical studies have revealed that binding of the proapoptotic BH3-only protein...

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Bibliographic Details
Published in:Biophys J
Main Authors: Liu, Xiaorong, Beugelsdijk, Alex, Chen, Jianhan
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2015
Subjects:
Proteins and Nucleic Acids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564842/
https://ncbi.nlm.nih.gov/pubmed/26331262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.043
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