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Proton beam radiation induces DNA damage and cell apoptosis in glioma stem cells through reactive oxygen species
Glioblastoma multiforme (GBM) is among the most lethal of human malignancies. Most GBM tumors are refractory to cytotoxic therapies. Glioma stem cells (GSCs) significantly contribute to GBM progression and post-treatment tumor relapse, therefore serving as a key therapeutic target; however, GSCs are...
保存先:
出版年: | Sci Rep |
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主要な著者: | , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Nature Publishing Group
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564801/ https://ncbi.nlm.nih.gov/pubmed/26354413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13961 |
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